Dr. Julian Ilgen
Working area(s)
Bachelor thesis 11/13 - 01/14, Master thesis 11/15 - 05/16, PhD thesis 10/16 - 02/21
Contact
Field of research
- Fast NMR-acquisition techniques for reaction monitoring
- homonuclear decoupled 1H NMR spectroscopy (pure shift NMR)
- pulse sequence development
Bachelor thesis
| Title | Temperature regulation within the NMR spectrometer via liquid crystalline phases |
| Group | Prof. Dr. C. M. Thiele |
| Place | Department of Chemistry, Technical University Darmstadt |
Master thesis
| Title | Investigation of the performance of pure shift-experiments in the presence of strong coupling |
| Group | Prof. Dr. C. M. Thiele |
| Place | Department of Chemistry, Technical University Darmstadt |
Dissertation
| Title | Development of a toolbox of NMR techniques for structure elucidation and their application |
| Group | Prof. Dr. C. M. Thiele |
| Place | Department of Chemistry, Technical University Darmstadt |
Prizes and awards
| 12/16 | Award of the Dr.-Anton-Keller-Foundation at Technische Universität Darmstadt |
| 09/17 | SMASH Student Stipend |
| 09/18 – | Ph. D. fellowship of the Studienstiftung des Deutschen Volkes |
| 09/19 | SMASH Student Stipend |
Publications
| 1 |
E. Procházková, A. Kolmer, J. Ilgen, M. Schwab, L. Kaltschnee, M. Fredersdorf, V. Schmidts, R. C. Wende, P. R. Schreiner, C. M. Thiele Uncovering Key Structural Features of an Enantioselective Peptide-Catalyzed Acylation Utilizing Advanced NMR Techniques Angew. Chem. 2016, 128, 15986–15991, Angew. Chem. Int. Ed. 2016, 55, 15754–15759. |
| 2 |
J. Ilgen, L. Kaltschnee, C. M. Thiele A pure shift experiment with increased sensitivity and superior performance for strongly coupled systems J. Magn. Reson. 2018, 286, 18-29. [JMR Most-read Publication Award in 2018] [Raw Data: DOI 10.23728/b2share.76f2f9e3f53d4fce90e2ac768102c34e] |
| 3 |
J. Ilgen, L. Kaltschnee, C. M. Thiele perfectBASH: Band-selective homonuclear decoupling in peptides and peptidomimetics Magn. Reson. Chem. 2018, 56, 918-933. [Raw Data: DOI 10.23728/b2share.688901f6e4fe4b92bd0238715c3186bb] |
| 4 |
D. Sinnaeve, J. Ilgen, M. E. Di Pietro, J. J. Primozic, V. Schmidts, C. M. Thiele, B. Luy Probing long-range anisotropic interactions – A general and sign-sensitive strategy to measure 1H-1H residual dipolar couplings as a key advance for organic structure determination Angew. Chem. Int. Ed. 2020, 59, 5316-5320; Angew. Chem. 2020, 132, 5354-5358. [Raw Data: DOI 10.6084/m9.figshare.11297651] |
| 5 |
J. Ilgen, J. Nowag, L. Kaltschnee, V. Schmidts, C. M. Thiele Gradient Selected Pure-Shift EASY-ROESY techniques facilitate the quantitative measurement of 1H,1H-distance restraints in congested spectral regions J. Magn. Reson. 2021, 324, 106900. [Preprint: PDF (opens in new tab) | SI (opens in new tab) ] |
| 6 |
J. J. Primozic, J. Ilgen, P. Maibach, M. Brauser, J. Kind, C. M. Thiele Pd-Catalyzed Asymmetric Allylic Alkylation of Cyclobutenes: From Double Inversion to Double Retention J. Am. Chem. Soc. 2023, 145, 15912-15923. |
Talks
| 1 |
PSYCHE-EASY-ROESY goes quantitative: Extraction of 1H,1H-distance restraints from overcrowded spectral regions SMASH 2019, Porto/Portugal, 09/19. |
Poster
| 1 |
S. Weißheit, J. Ilgen, A. Beimel, R. Kümmerle, P. Lendi, R. Hensel, D. Moskau, V. Schmidts, C. M. Thiele Regulation of Quadrupolar Splittings in NMR Experiments on Anisotropic Samples GDCh FGMR 37th Annual Discussion Meeting, Darmstadt, 09/15. |
| 2 |
S. Weißheit, J. Ilgen, A. Beimel, R. Kümmerle, P. Lendi, R. Hensel, D. Moskau, V. Schmidts, C. M. Thiele Regulation of Quadrupolar Splittings in NMR Experiments on Anisotropic Samples SMASH 2015, Baveno/Italy, 09/15. |
| 3 |
J. Ilgen, L. Kaltschnee, C. M. Thiele A variant to Zangger-Sterk decoupling with improved sensitivity Euromar 2016, Aarhus/Denmark, 07/16. |
| 4 |
J. Ilgen, L. Kaltschnee, C. M. Thiele A Zangger-Sterck based pure shift experiment not requiring full spatial separation of coupling partners for studies of peptidomimetic oligomers ENC 2017, Pacific Grove/CA/USA, 03/17. |
| 5 |
J. Ilgen, L. Kaltschnee, C. M. Thiele Novel Developments in Pure Shift NMR Using Perfect-Echo and Zangger-Sterk SMASH 2017, Baveno/Italy, 09/17. |
| 6 |
J. Ilgen, L. Kaltschnee, C. M. Thiele Ultrahigh resolution EASY-ROESY spectra with improved spectral quality GDCh FGMR 40th Annual Discussion Meeting, Leipzig, 09/18. |
| 7 |
J. Ilgen, J. Nowag, L. Kaltschnee, C. M. Thiele PSYCHE-EASY-ROESY goes quantitative: Extraction of 1H,1H-distance restraints from overcrowded spectral regions SMASH 2019, Porto/Portugal, 09/19. |
