Seminars
SS 2009
| 26.03.09 | Thomas Kramer | Part B, Ch. 9 Finding a lead: |
| 16.04.09 | Alexander Boländer | Part B, Ch. 10 Drug Design, PNAS Zhang Interprotofilament |
| 23.04.09 | Nicole Höttecke | Part B, Ch. 11 Optimization |
| 30.04.09 | Daniel Kieser | Part B, Ch. 12 Development |
| 07.05.09 | Andrea Zall |
Part B, Ch. 13 QSAR How to beat an alcohol problem Nature 2008, 456, p.711, p.77 |
| 14.05.09 | Azadeh Nazari | Part C, Ch. 14 Combichem |
| 28.05.09 | Koolman | Part C, Ch. 15 Compuchem |
| 04.06.09 | B.I. | Spinnenseide |
| 09.06.09 | Merck Lecture 4x | |
| 18.06.09 | O. Müller | Part D, Ch. 17 Antivirals |
| 25.06.09 | BMBF Summerschool | |
| 02.07.09 | Thomas Kramer | Part D, Ch. 18 Anticancer & Byrostatin in Nature 2008, 456, 485 highlight |
| 09.07.09 |
F. Gerstmann F. Lo Monte |
Part D, Ch. 16 Antibacterials Therapeutic application of histone deacetylase inhibitors for CNS |
| 28.08.09 | Auguste Deter Gedächtnis-Seminar: Tau entangles in the trees | |
| 30.08.-03.09.09 | GDCh-Wissenschaftsforum, Frankfurt |
WS 2009/10
| 01.10.09 | Nicole Höttecke | Part D, Ch. 19 Cholinergics |
| 08.10.09 | Alexander Boländer | Part D, Ch. 20 Adrenergics |
| 15.10.09 | Boris Schmidt | Neuroleptika |
| 29.10.09 | Fabio Lo Monte | Part D, Ch. 21 Opium analgesics, Abbot ABT594 + Epibatidin |
| 19.11.09 | Daniel Kieser | Part D, Ch. 22 Antiulcer |
| Totalsynthesen, Synthesemethoden, Biochemie | ||
| 26.11.09 | Thomas Kramer | Akt Inhibitor X: linked via mTOR to GSK3? |
| 05.11.-06.11.09 | N. Höttecke, D. Kieser, F. Lo Monte | Neuro GSK3 |
| 17.12.09 | X-Mas Seminar | |
| 14.01.10 | BMBF Seminar München | |
| 21.01.10 |
Andrea Zall Azadeh Nazari |
Total Synthesis of Hirsutellone B. Angew. Chem. 2009, 121, 7002 Tricyclische Antidepressive. ChiuZ 2008, 206 & Carbozolsynthese-Review H.-J. Knöler Chem. Rev. 2002, 4303 Top Curr Chem |
SS 2010
| Imaging and Lipids | ||
| 15.04.10 | Dr. S. Kolb | CDC25 + An Efficient Method Based on the Photothermal Effect for the Release of Molecules from Metal Nanoparticle Surfaces. Angew. Chem. 2009, 4230 Nature 2010 Hyman in Press |
| 22.04.10 | Jiamin Gu | Imaging Neurodegeneration in Parkinsons' Disease (opens in new tab). Biochimica et Biophysica Acta 2009, 457, 573 |
| 29.04.10 | Binia Thomaszewski | Drug-Phospholipid Interaction. ChemMedChem 2009, 4(8), 1224 MCT1 Transporter and BBB |
| 06.05.10 | Andrea Zall | Chlorinated Lipids associated with seafood poisoning.Nature 2009, 457, 548, Nature 2009, 457, 573 |
| 20.05.10 | Daniel Kieser | Hochauflösende Mikroskopie mit kleinen organischen Farbstoffen. Angew. Chemie 2009, 121, 7036 |
| 27.05.10 | Alexander Boländer |
Labelling of Terminal Cysteine Residues. Angew. Chem. 2009, 121, 9838 Photoswitching of Cyanine Dyes. JACS 2010 |
| 10.06.10 | Thomas Kramer | nicht ATP-kompetitive Kinase-Inhibitoren |
| 17.06.10 | Azadeh Nazari | |
| 24.06.10 | Eva Fuchs | BACE Inhibitoren |
| 01.07.10 | Fabio Lo Monte | Resveratrol and Sirtuins. C&EN 2009, 14.12. |
| 08.07.10 | Upendra Anumala | STED/PALM Microscopy – switchable dyes |
WS 2010/11
| 07.10.10 |
Jiamin Gu Matthias Fach |
(8+2) Cycloaddition – Review, Application and Optimisation GSK3 Inhibition |
| 04.11.10 | Binia Thomaszewski |
plos one 2010, 5, e9505 S.J. Soscia et al. Abeta is an antimicrobial peptide |
| 18.11.10 | Daniel Kieser | AD Imaging. Okamura et al. J. Neuroscience 2005, 25, 10857 |
| 25.11.10 | Eva Naumann |
Auguste Deter Einweisungssymposium! HDAC6 Inhibitoren: Leitstrukturen, Synthese und Selektivität |
| 02.12.10 | X-Mas Seminar | |
| 20.01.11 | Alexander Boländer | Parkinson's Disease: Diagnostics & Therapy. Nature 2010, 466, S1 (26.08.), reMynd |
| 27.01.11 | Thomas Kramer | LRRK2 Inhibitors |
| 27.01.11 | Daniel Kieser | AD Imaging |
| 03.02.11 | Andrea Zall | Photocrosslinking to proteins |
SS 2011
| 12.05.11 |
Fabio Lo Monte Karl Gatterdam |
Z-Enolether synthesis GSM |
| 19.05.11 |
Constantin Voss Jiamin Gu |
GrK SB – Assayplan und Referenzstubstanzen Drug Membrane Interactions. J.K. Seydel focus on Nile red |
| 16.06.11 |
Eva Naumann Upendra Anumala |
HDAC 2/6 Assays, Tiermodelle und neue Zn-koordinierende Motive J-Aggregates. Angew. Chemie 2011, 3376 |
| 22.06.11 | Dennis Bensinger | Neue Motive für das 20 S Proteasom. E. J. Med. Chem 2011 |
| 11.08.11 | A. Nazari, M. Brodrecht, J. Pilakoswki |
Trifluoromethylation, Angew. Chemie. 2011, 3877 B.Sc. Vorträge |
| 18.08.11 |
B. Thomaszewski Andrea Zall |
APOE Strukturen und Ab, J. Biol.Chem. 2007, 1073, 281. PEG beim Wirkstofftransport. Angew. Chem. 2010, 6430 |
| 25.08.11 | Thomas Kramer | Daniel Rauh: Stabilizing Inactive Kinases. Arch. Pharm, 2010, 3434, 193, NCTL, 2010, 118 |
| 01.09.11 | Alexander Boländer | B. Yousefi et al. J. Med. Chem. 2011, 54(4), 949-956 Öancet 2011, Florbetaben, Neuroimage 2011, 54, S204-217 |
WS 2011/12
| 06.10.11 | Sarah Albrecht | Transparente Fische für die Fluoreszenzmikroskopie, Scale: transparent mouse brain. Nature Neuroscience 2011 |
| 20.10.11 | Fabio Lo Monte | Aromatische Ringe in chemischer und biologischer Erkennung. Angew.Chemie,2011, 4908 |
| 17.11.11 | Alexander Boländer |
2-Photon absorption properties of fluorescent proteins. Nature Methods,2011, 8, 393 Characterization of prefibrillar tau oligomers… J.Biol.Chem2011 |
| 24.11.11 | Stefan Göring |
MKK4, a druggable target? Mol Cell Biochem Czech et al 2011 Pd-kat Kreuzkupplung Heteroarene. Angew. Chem. 2001, 123, 7618 Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 2011, 477, 107 |
| 24.11.11 | Thomas Kramer | Praktische Eintopfsynthese. Angew. Chem. 2011, 7428 |
| 01.12.11 | Andrea Zall | Crystal structure of the ab p3. J. Neuroscience 2011, 31, 1419 |
| 01.12.11 | Constantin Voss | Fluorescent and luminescent probes for the detection of ROS.Chem.Soc.Rev. 2011, 40, 4783 |
| 08.12.11 | Jiamin Gu |
Dye-sensitized solar cells. Chemistry EJ 2011 Cynain dye T-284 and synuclein. J. Fluoresence 2010, 20, 1267 |
| 12.01.12 | Eva Naumann |
Störung von Histon-Ablesern. Angew. Chem. 2011, 123, 5921 Charcot-Marie Tooth disease |
| 12.01.12 | Upendra Anumala | Light microscopy with doghnut modes. Angew. Chem. 2011, 5274 |
| 19.01.12 | Binia Thomaszewski |
Kristalline Lipiddomänen. Angew. Chem. 2011, 123, 3700 Protein membrane anchorage. Angew. Chem. 2011, 123, 6327 |
| 02.02.12 | Azadeh Nazari | Dyrk1A Inhibitors SAR. PlosOne 2011, e19264 |
SS 2012
| 19.04.12 | Stefan Göring | Synuclein Dyes. Histology of Parkinson's disease |
| 26.04.12 |
Christoph Scholz Matthias Fach |
Multiple myeloma and the proteasome. Nature 2011, 480, 833ff Proteasom regulation. Nature 2012, 482, 170 & 186 FLT3 Inhibition Targeting protein kinases in central nervous system disorders Nature Drug Discovery 2009, 8, 892 |
| 10.05.12 | M. BME | Dyrk1 |
| 24.05.12 | Constantin Voss |
Die Chemie und der Wurm Angew. Chem. 2011, 4870 Tumor bearing chick-embryo J. Rad. Res. 2011, 52, 208 Cyclin D1 multitasks Nature 2011, 474, 171 + 230 Cyclin D1 ligands, antagonists? Hyper I-III ROS sensitive proteins |
| 31.05.12 | ||
| 07.06.12 |
Eva Naumann Theresa Neumann |
Amphoterin B and analogues Protein templated Click chemistry Angew. Chem. 2010, 122, 6969 Metabolic labelling |
| 14.06.12 | Upendra Anumala |
Trifluromethylation of arenes and heteroarenes by means of photoredox catalysis Nature 2011, 224 Proteasome Inhibition |
| 14.06.12 | Binia Drung | P. Knochel Regio- und chemoselektive Metallierung Angew. Chem. 2011, 9968 |
| 21.06.12 |
Jiamin Gu Upendra Anumala |
Review Jeff Kuret, synuclein dyes, J/H, Vokova et al. Shuttle medicated drug delivery to the brain. Angew. Chem. 2011, 50, 7998 |
| 28.06.12 | Christoph Scholz | Proteasom-Inhibitoren |
| 05.07.12 | Matthias Fach | Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hing Binding Mode. ACS Med. Chem. Lett. 2012 |
| 12.07.12 | Azadeh Nazari |
WS 2012/13
| 08.11.12 | Upendra Anumala | H.C. Kolb: A highly selective and specific PET Tracer for Imaging of Tau Pathologies. J. Alz. Dis. 2012, 31, 1-12 |
| 15.11.12 | Prof. Kloetzel | 17.00-18.30 Graduiertenkolleg, FB Biologie |
| 22.11.12 | Jiamin Gu | Jeff Kuret et al: Ligand electronic properties modulate tau filament binding site density. sciencedirect |
| 29.11.12 | PD Dr. Gaipl | 17.00-18.00 Uhr Graduiertenkolleg, FB Biologie |
| 29.11.12 | Valeria Barbosa | Carbolines from Arylazides Angew. Chem. 2012, 124, 6022 |
| 13.12.12 | PD Dr. Gaipl | 17.00-18.00 Uhr Graduiertenkolleg, FB Biologie |
| 17.01.13 | Stefan Göring |
Validation of ITD mutations in FLT3 as a therapeutic target Nature 2012, 485, 260 Reagentless Oxidative Folding Angew. Chem. 2012, 124, 5678 Strategic use of non-native diselenide bridges Angew. Chem. 2012, 124, 5683 |
| 24.01.13 | Binia Drung |
Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding Mode. ACS Med. Chem. Lett. 2012 Catalyst-Controlled Chemoselective Arylation of 2-Aminobenzimidazoles Angew. Chem. Chem. 2012 |
| 24.01.13 |
Eva Naumann Theresa Neumann |
A breach in the Blood Brain Barrier. Nature 2012, 485, 451 + 452 Ohne dirigierende Gruppen: übergangsmetallkatalysierte C-H-Aktivierung Angew. Chem. 2012, F. Glorius |
| 31.01.13 | Constantin Voss |
Spurlose Triazolsynthese. Angew. Chem. 2012, 124, 5437 Activation of remote meta-C-H bonds assisted by an en-on template Nature 2012, 486, 518 |
| 07.02.13 | Boris Schmidt | Fragment based Approaches in Drug Discovery and Chemical Biology. Biochemistry 2012, 51 (25), 4990-5003 |
| 14.02.13 | Dennis Bensinger | Chemical Protein Synthesis by Chemoselective a-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline Angew. Chem. 2012, 5114 |
SS 2013
| 11.04.13 | Steven Smith | M.Sc. Thesis: Novel core motics for kinase inhition |
| 18.04.13 | Theresa Neumann | M.Sc Thesis: Improved GSK3 Inhibitors |
| 25.04.13 | Parul Goel | Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics eLife 2012 |
| 25.04.13 | Stefan Göring |
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 Nature 2012, 491, 603 Demystifying Brain Penetration in Central Nervous System Drug Discovery. J. Med. Chem, 2013, 56, 2-12 |
| 02.05.13 | Eva Naumann |
Structure of a presenilin family intramembrane aspartane protease Nature 2013, 493, 56 34 Modulators of -Secretase Activity Can Facilitate the Toxic Side-Effects and Pathogenesis of Alzheimer's Disease. PlosOne 2013 |
| 02.05.2013 | Binia Drung | Wechselwirkungen zwischen amyloidogenen Proteinen und Membranen. Angew. Chem. 2010, 122, 5760-5788 |
| 16.05.2013 | n. n. | Theresa Leutzsch |
| 23.05.2013 | Oberseminar | |
| 03.06.-07.06.2013 |
Binia Drung Constantin Voss |
GrK Retreat, Hirschegg |
| 13.06.2013 |
Constantin Scholz Theresa Neumann EU Horizon 2020 |
Bacterial proteolytic complexes Nature Rev. Drug Dis. 2012, 11, 77 JNK3 as a new target in AD? Nature Drug Discovery 2012, 11, 829 Synthese aromatischer Nitrile mithilfe nichtmetallischer CN-Quellen Angew. Chem. 2012, 124, 2114. Darmstadtium 13.30-18.30 Uhr |
| 20.06.2013 |
Constantin Voss Karen Voehringer F. Anders/T. Lotz |
Reducing safety-related drug attrition: The use of in vitro pharmalogical profiling Nature Reviews Drug Discovery 2012, 11, 909-922 Botox Assay MBME Abschlussvortrag: iProteasom |
| 27.06.2013 | V. Spieler, J. G. | M. BME Abschlussvortrag: NEK1 |
| 04.07.2013 | J. Pilakowsky | M. BME Abschlussvortrag: NEK1, Rhomboid |
| 18.07.2013 | Liebig, Babel | M. BME Abschlussvortrag: FLT3 |
| 01.09.-04.09.2013 | GDCh Tagung, Darmstadt |
WS 2013/14
| 31.10.2013 |
Theresa Neumann Binia Drung |
Metalated Indoles, Indazoles, Benzimidazoles and Azaindoles and their Synthetic Applications. Synthesis 2013, 2343 Self-propagation of pathogenic protein aggregates in neurodegenative disease Nature 2013, 501, 45 |
| 14.11.2013 | Johannes Pilakowski | Master Thesis Presentation |
| 28.11.2013 |
Constantin Voss Christoph Scholz |
ALS – Motorneuron degradation & targets for drug development, TDP-43 |
| 09.12.-11.12.2013 |
Binia Drung Constantin Voss |
GrK Retreat, Trifels |
| 05.12.2013 | Parul Goel | Rhomboid Inhibitors Own Results |
| 19.12.2013 | X-Mas Seminar | |
| 16.01.2014 | Eva Naumann | Abschlussvortrag |
| 23.01.2014 | Dennis Bensinger | Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines. Nature 2013, 501, 195. |
| 30.01.2014 | Stefan Göring | Platforms for antibiotic discovery DOI: 10.1038/NRD3975 |
| 06.02.2014 | ||
| 13.02.2014 |
