A detailed understanding of the reaction kinetics enables you to adjust a given reaction for special requirements. An industrial chemist is interested in the conversion rate of his reaction, while a pharmaceutical chemist wants to know in which quantity possible by-products are build. Depending on the key aspect and the reaction the problem differs, but for an increase of efficiency knowledge of the kinetic parameters is inevitable.
NMR spectroscopy is one possibility for extracting these kinetic properties. It is a non-destructive and (under special circumstances) quantitative method, which permits the study of a reaction at minutes or hour time-scales.
In our group we observe the photochromic reaction of a spiropyrane and the olefin metathesis reaction of a Grubbs Hoveyda complex via single-scan 1H-NMR spectra.
Coworker on that area
|Dr.-Ing. Christiane Wolff|