Lukas Kaltschnee

Dr. Lukas Kaltschnee


Arbeitsgebiet(e)

  • Masterthesis 10/11 - 04/12
  • Promotion 06/12 - 08/16

Mehr Informationen

Lukas hat am 09. August 2016 promoviert. Herzlichen Glückwunsch!

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Forschungsgebiet

  • J-entkoppelte „pure-shift“ Protonenspektren

Ausbildung

08/92 – 07/96 Grundschule, Frankfurt a. M. und Friedrichsdorf
08/96 – 07/05 Gymnasialer Zweig, Philipp-Reis-Schule, Friedrichsdorf
09/05 – 05/06 Zivildienst, Frankfurter Verein für soziale Heimstätten e.V.
10/06 – 03/10 Chemiestudium B. Sc., Technische Universität Darmstadt, Darmstadt
09/08 – 07/09 ERASMUS-Auslandsstudium, École Polytechnique Fédérale de Lausanne, Lausanne (Schweiz)
04/10 – 04/12 Chemiestudium M. Sc., Technische Universität Darmstadt, Darmstadt
Schwerpunktfach Physikalische Chemie
06/11 – 09/11 Externe Hauptvertiefung, Max-Planck-Institut für Polymerforschung, Mainz, bei F. Laquai
10/11 – 04/12 Master-Thesis, Technische Universität Darmstadt, Darmstadt
06/12 – 08/16 Promotion, Technische Universität Darmstadt, Darmstadt
07/14 – 09/14 Forschungsaufenthalt, University of Manchester, Großbrittanien, bei Gareth A. Morris
seit 09/16 Postdoc, NIDDK/NIH, Bethesda, MD, USA, bei Adriaan Bax

Bachelorthesis

Titel Effect of Coadsorbents on the Performance of Dye Sensitized Solar Cells
Arbeitskreis Prof. Dr. M. Grätzel
Ort Faculté des Sciences de Base, École Polytechnique Fédérale de Lausanne; eingereicht am Eduard-Zintl-Institut für Anorganische und Physikalische Chemie, Technische Universität Darmstadt

Masterthesis

Titel Untersuchungen zur Quantifizierung 1H-entkoppelter protonendetektierter Experimente
Arbeitskreis Prof. Dr. C. M. Thiele
Ort Clemens-Schöpf-Institut für Organische Chemie und Biochemie, Fachbereich Chemie, Technische Universität Darmstadt

Dissertation

Titel Development and Evaluation of Experiments for Pure Shift Solution-State Magnetic Resonance Spectroscopy
Arbeitskreis Prof. Dr. C. M. Thiele
Ort Clemens-Schöpf-Institut für Organische Chemie und Biochemie, Fachbereich Chemie, Technische Universität Darmstadt

Preise und Auszeichnungen

01/13 – 12/14 Promotionsstipendium der Merck'schen Gesellschaft für Kunst und Wissenschaft e.V.
09/16 – 02/18 P.R.I.M.E. Fellowship des Deutschen Akademischen Auslandsdienstes (DAAD)
02/17 Kurt-Ruths-Preis der Technischen Universität Darmstadt

Vorträge

1 Improving Signal Separation for Oligomeric Structures in Pure Shift HSQC Spectra
GDCh FGMR 37th Annual Discussion Meeting, Darmstadt, 09/15. (upgraded poster)
2 CLIP-COSY: Rapid Acquisition of COSY-Type Correlation Spectra with In-Phase Signal Character
5th Annual Practical Applications of NMR in Industry Conference (PANIC 2017), Hilton Head Island/SC/USA, 02/17. (invited talk)

Publikationen

1 A. Kolmer, L. Kaltschnee, V. Schmidts, L. H. Peeck, H. Plenio, C. M. Thiele
The influence of electronic modifications on rotational barriers of bis-NHC-complexes as observed by dynamic NMR spectroscopy
Magn. Reson. Chem. 2013, 51, 695–700.
2 I. Timári, L. Kaltschnee, A. Kolmer, R. W. Adams, M. Nilsson, C. M. Thiele, G. A. Morris, K. E. Kövér
Accurate determination of one-bond heteronuclear coupling constants with “pure shift” broadband proton-decoupled CLIP/CLAP-HSQC experiments
J. Magn. Reson. 2014, 239, 130-138.
3 L. Kaltschnee, A. Kolmer, I. Timári, V. Schmidts, R. W. Adams, M. Nilsson, K. E. Kövér, G. A. Morris, C. M. Thiele
„Perfecting“ pure shift HSQC: full homodecoupling for accurate and precise determination of heteronuclear couplings
Chem. Commun. 2014, 50, 15702-15705.
4 M. R. M. Koos, G. Kummerlöwe, L. Kaltschnee, C. M. Thiele, B. Luy
CLIP-COSY: A Clean Inphase Experiment for Rapid Acquisition of COSY-type Correlations
Angew. Chem. 2016, 128, 7785-7789, Angew. Chem. Int. Ed. 2016, 55, 7655-7659.
5 L. Kaltschnee, K. Knoll, V. Schmidts, R. W. Adams, M. Nilsson, G. A. Morris, C. M. Thiele
Extraction of Distance Restraints from Pure Shift NOE experiments
J. Magn. Reson. 2016, 271, 99-109.
6 I. Timári, L. Kaltschnee, M. H. Raics, F. Roth, N. G. A. Bell, R. W. Adams, M. Nilsson, D. Uhrín, G. A. Morris, C. M. Thiele, K. E. Kövér
Real-time broadband proton-homodecoupled CLIP/CLAP-HSQC for automated measurement of heteronuclear one-bond coupling constants
RSC Adv. 2016, 6, 87848-87855.
7 J. Kind, L. Kaltschnee, M. Leyendecker, C. M. Thiele
Distinction of trans-cis photoisomers with comparable optical properties in multiple-state photochromic systems – Examining a molecule with three azobenzenes via in situ irradiation NMR
Chem. Commun. 2016, 52, 12506-12509.
8 E. Procházková, A. Kolmer, J. Ilgen, M. Schwab, L. Kaltschnee, M. Fredersdorf, V. Schmidts, R. C. Wende, P. R. Schreiner, C. M. Thiele
Uncovering Key Structural Features of an Enantioselective Peptide-Catalyzed Acylation Utilizing Advanced NMR Techniques
Angew. Chem. 2016, 128, 15986–15991, Angew. Chem. Int. Ed. 2016, 55, 15754–15759.
9 J. Ilgen, L. Kaltschnee, C. M. Thiele
A pure shift experiment with increased sensitivity and superior performance for strongly coupled systems
J. Magn. Reson. 2018, 286, 18-29. [JMR Most-read Publication Award in 2018]
10 J. Ilgen, L. Kaltschnee, C. M. Thiele
perfectBASH: Band-selective homonuclear decoupling in peptides and peptidomimetics
Magn. Reson. Chem. 2018, 56, 918-933.

Poster

1 L. Kaltschnee, V. Schmidts, J. A. Aguilar, A. A. Colbourne, R. W. Adams, M. Nilsson, G. A. Morris, C. M. Thiele
Cross-relaxation rates from pure shift NOESY spectra
EUROMAR 2012, Dublin/Ireland, 07/12.
2 A. Kolmer, L. Kaltschnee, M. Haus, V. Schmidts, L. H. Peeck, H. Plenio, C. M. Thiele
The influence of electronic modifications on dynamics and reactivity of Bis-NHC-complexes as observed by NMR spectroscopy
EUROMAR 2012, Dublin/Ireland, 07/12.
3 L. Kaltschnee, V. Schmidts, J. A. Aguilar, A. A. Colbourne, R. W. Adams, M. Nilsson, G. A. Morris, C. M. Thiele
Cross-relaxation rates from pure shift NOESY spectra
GDCh FGMR 34th Annual Discussion Meeting, Halle, 09/12.
4 A. Kolmer, L. Kaltschnee, M. Haus, V. Schmidts, L. H. Peeck, H. Plenio, C. M. Thiele
The influence of electronic modifications on dynamics and reactivity of Bis-NHC-complexes as observed by NMR spectroscopy
GDCh FGMR 34th Annual Discussion Meeting, Halle, 09/12.
5 L. Kaltschnee, V. Schmidts, J. A. Aguilar, A. A. Colbourne, R. W. Adams, M. Nilsson, G. A. Morris, C. M. Thiele Interatomic Distance Measurements Using Pure Shift NOE Experiments
54th Experimental Nuclear Magnetic Resonance Conference, Asilomar/California/USA, 04/13.
6 L. Kaltschnee, V. Schmidts, J. A. Aguilar, A. A. Colbourne, R. W. Adams, M. Nilsson, G. A. Morris, C. M. Thiele Interatomic Distance Measurements Using Pure Shift NOE Experiments
EUROMAR 2013, Crete/Greece, 07/13.
7 L. Kaltschnee, A. Kolmer, I. Timári, R. W. Adams, M. Nilsson, K. E. Kövér, G. A. Morris, C. M. Thiele
Pure Shift HSQC measurements with perfectBIRD decoupling
EUROMAR 2013, Crete/Greece, 07/13.
8 I. Timári, L. Kaltschnee, A. Kolmer, R. W. Adams, M. Nilsson, C. M. Thiele, G. A. Morris, K. E. Kövér Measuring one-bond heteronuclear coupling constants with improved resolution
EUROMAR 2013, Crete/Greece, 07/13.
9 L. Kaltschnee, A. Kolmer, I. Timári, R. W. Adams, M. Nilsson, K. E. Kövér, G. A. Morris, C. M. Thiele
Pure Shift HSQC measurements with perfectBIRD decoupling
GDCh FGMR 35th Discussion Meeting, Frauenchiemsee, 09/13.
10 L. Kaltschnee, A. Kolmer, I. Timári, R. W. Adams, M. Nilsson, K. E. Kövér, G. A. Morris, C. M. Thiele
Pure Shift HSQC measurements with perfectBIRD decoupling
SMASH 2013, Santiago de Compostela/Spain, 09/13.
11 L. Kaltschnee, A. Kolmer, I. Timári, R. W. Adams, M. Nilsson, K. E. Kövér, G. A. Morris, C. M. Thiele Applications of pure shift HSQC experiments with „perfectBIRD“ decoupling
EUROMAR 2014, Zurich/Switzerland, 07/14.
12 Y. E. Moskalenko, V. Bagutski, L. Kaltschnee, C. M. Thiele
PDMS Gels as Alignment Media for NMR/RDC Analysis of Small Organic Molecules
ORCHEM 2014, Weimar, 09/14.
13 L. Kaltschnee, T. Imhof, K. Pulka-Ziach, Yu. E. Moskalenko, W. Bermel, C. M. Thiele
Improving Signal Separation for Oligomeric Structures in Pure Shift HSQC Spectra
EUROMAR 2015, Prague/Czech Republic, 07/15.
14 J. Ilgen, L. Kaltschnee, C. M. Thiele,
A variant to Zangger-Sterk decoupling with improved sensitivity
EUROMAR 2016, Aarhus/Denmark, 07/16.
15 J. Kind, L. Kaltschnee, M. Leyendecker, C. M. Thiele
Monitoring a Four-State Photoisomerization Process via In Situ Irradiation NMR Spectroscopy
5th Annual Practical Applications of NMR in Industry Conference (PANIC 2017), Hilton Head Island/SC/USA, 02/17.
16 J. Ilgen, L. Kaltschnee, C. M. Thiele
A Zangger-Sterck based pure shift experiment not requiring full spatial separation of coupling partners for studies of peptidomimetic oligomers
ENC 2017, Pacific Grove/CA/USA, 03/17.
17 J. Kind, L. Kaltschnee, M. Leyendecker, C. M. Thiele
Monitoring a Four-State Photoisomerization Process via In Situ Irradiation NMR Spectroscopy
ENC 2017, Pacific Grove/CA/USA, 03/17.