Dr. Yulia Moskalenko

Dr. Yulia Moskalenko

Arbeitsgebiet(e)

  • Postdoc 06/12 - 02/15

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Forschungsgebiet

  • Synthese von α- und β-Aminosäuren, -derivaten und -peptide
  • Herstellung und NMR Evaluierung von Orientierungsmedien für RDC-Analyse
  • NMR-basierte Strukturanalyse von kleinen organischen Molekülen

Ausbildung / Studium

02/04 – 09/08 Promotion, Laboratory of Peptide and Microspheres Synthesis, Institute of Macromolecular Compounds, Russian Academy of Sciences (IMC RAS), St. Petersburg, Russland.
10/08 – 05/12 Wissenschaftliche Mitarbeiterin, NMR Spectroscopy Group, IMC RAS, St. Petersburg, Russland.

Masterthesis

Titel Synthesis and application of Human Calcitonin Hormone short analogues in treatment of human diseases by gene delivery
Arbeitskreis Prof. Sergey Burov
Ort Department of Industrial Drug Technology, Chemical Pharmaceutical Academy, St. Petersburg, Russland

Dissertation

Titel N-Amidino-amino Acids and their Applications in Synthesis of Polypeptides
Arbeitskreis Prof. Sergey Burov
Ort IMC RAS, St. Petersburg, Russland

Preise und Auszeichnungen

04 M. Sc. in Chemie mit Auszeichnung
06 Reisestipendium für 29. European Peptide Symposium
08 Reisestipendium für 30. European Peptide Symposium
seit 08/08 Mitglied der European Peptide Society
09 – 10 Stipendium des Russian President Council for young scientists: Development of comprehensive solution and solid-state NMR method for structural analysis of polymer systems

Publikationen

1 S. V. Burov, Yu. E. Moskalenko, E. F. Panarin
Synthesis of N-[N1-(2,4,6-Trimethylphenylsulfonyl)-carbamimidoyl]-L-proline
Russ. J. Gen. Chem. 2006, 76, 665-667.
2 S. Burov, Yu. E. Moskalenko, M. Leko, M. Dorosh, Z. Shkarubskaya, E. Panarin
Derivatives of N-Amidino-proline and their use in conventional and solid phase peptide synthesis
Russ. J. Bioorg. Chem. 2006,32, 509-516.
3 Yu. E. Moskalenko, I. N. Dementieva, M. I. Kadinskaya, S. V. Burov
The influence of RGD peptides analogues and low-power light-emitting diode irradiation on ADP-induced platelet aggregation
Clinical Laboratorial Concilium 2007, 18, 36-40 (in Russian).
4 S. Burov, Yu. E. Moskalenko, M. Dorosh, Z. Scharubskaya, E. Panarin
Incorporation of N-amidino-pyroglutamic acid into peptides using intramolecular cyclization of α-guanidinoglutaric acid
J. Pept. Sci. 2009, 15, 760-766.
5 Yu. E. Moskalenko, N. N. Shevchenko, M. V. Mokeev, A. Yu. Men’shikova, A. V. Yakimansky, A. V. Gribanov
Solid-state 13C NMR spectroscopic examination of lower alcohol vapor sorption by cross-linked poly(methyl methacrylate) particles
Russ. J. Appl. Chem. 2010, 83, 400-405.
6 N. A. Bokach, N. P. Konovalova, Y. Wang, Yu. E. Moskalenko, A. V. Gribanov, V. Yu. Kukushkin
One-end nucleophilic addition of di- and triamines to PtIV coordinated nitriles as an entry to (amidine)PtIV complexes bearing pendant NH2-groups
Dalton Trans. 2010, 39, 4619-4623.
7 A. Yu. Men'shikova, Yu. E. Moskalenko, A. V. Gribanov, N. N. Shevchenko, V. V. Faraonova, A. V. Yakimanskii, M. Ya. Goikhman, N. L. Loretsyan, A. V. Koshkin, M. V. Alfimov
Sorption of vapors of aromatic compounds by cross-linked polymer particles containing luminophores: A spectroscopic study
Russ. J. Appl. Chem. 2010, 83, 1997-2005.
8 Yu. E. Moskalenko, A. Yu. Men'shikova, N. N. Shevchenko, V. V. Faraonova, A. V. Gribanov
A 1H NMR study of Nile Red solvation
High Energy Chem. 2011, 45, 183-187.
9 M. Käldström, N. Kumar, M. Tenho, M. Mokeev, Yu. E. Moskalenko, D. Murzin
Catalytic transformations of birch kraft pulp, ACS Catal. 2012, 2, 1381-1393.
10 Yu. E. Moskalenko, V. Bagutski, C. M. Thiele
Chemically synthesized and cross-linked PDMS as versatile alignment medium for organic compounds
Chem. Commun. 2017, 53, 95-98. [Inside Front Cover]

Ausgewählte Poster

1 N-Amidino-proline derivatives and their application in peptide synthesis, Transatlantic Frontiers of Chemistry Meeting, 29th European Peptide Symposium, Gdansk/Poland, 09/06.
2 Synthesis and conformational analysis of new gonadotropin-releasing hormone (GnRH) analogues, VIth International Symposium “Molecular Order and Mobility in Polymer Systems”, St. Petersburg/Russia, 06/08.
3 Synthesis of peptides containing five-member cyclic N-amidino-amino acids, 30th European Peptide Symposium, Helsinki/Finland, 08/08.
4 Conformational isomerisation of PtII-coordinated 1,3,5-triazine in solution and solid state, EUROMAR 2010, Florence/Italy, 07/10.
5 Drug-polymer interactions of water-soluble chitosan: UV/VIS and NMR spectral investigation, 10th Baltic Polymer Symposium, Palanga/Lithuania, 09/10.
6 W. Blum, Yu. E. Moskalenko, C. M. Thiele, Design, Synthesis and Evaluation of β-peptides in NMR-RDC-Structural Analysis, Wissenschaftsforum Chemie 2013, Darmstadt, 09/13.
7 Yu. E. Moskalenko, W. Blum, C. M. Thiele, β-Peptide Liquid Crystalline Phases for NMR/RDC Structural Analysis of Organic Molecules, PepMat 2013: Peptide Materials for Nanotechnology and Biomedicine, Sorrento/Italy, 10/13.
8 Yu. E. Moskalenko, K. Pulka-Ziach, C. M. Thiele, Desing of Oligoureas Containing Aromatic Side-Chains, 33rd European Peptide Symposium, Sofia/Bulgaria, 09/14.
9 Yu. E. Moskalenko, V. Bagutski, L. Kaltschnee, C. M. Thiele, PDMS Gels as Alignment Media for NMR/RDC Analysis of Small Organic Molecules: Synthesis and Evaluation, ORCHEM, Weimar, 09/14.
10 L. Kaltschnee, T. Imhof, K. Pulka-Ziach, Yu. E. Moskalenko, W. Bermel, C. M. Thiele, Improving Signal Separation for Oligomeric Structures in Pure Shift HSQC Spectra, EUROMAR 2015, Prague/Czech Republic, 07/15.

Vorträge

1 Physicochemical Processes in Polymer Architectures Seen by NMR Spectroscopy at Various Dimension Levels, VIIth International Symposium “Molecular Mobility and Order in Polymer Systems”, St. Petersburg/Russia, 06/11.