Dr. Yulia Moskalenko
Arbeitsgebiet(e)
Postdoc 06/12 - 02/15
Kontakt
Forschungsgebiet
- Synthese von α- und β-Aminosäuren, -derivaten und -peptide
- Herstellung und NMR Evaluierung von Orientierungsmedien für RDC-Analyse
- NMR-basierte Strukturanalyse von kleinen organischen Molekülen
Ausbildung / Studium
| 02/04 – 09/08 | Promotion, Laboratory of Peptide and Microspheres Synthesis, Institute of Macromolecular Compounds, Russian Academy of Sciences (IMC RAS), St. Petersburg, Russland. |
| 10/08 – 05/12 | Wissenschaftliche Mitarbeiterin, NMR Spectroscopy Group, IMC RAS, St. Petersburg, Russland. |
Masterthesis
| Titel | Synthesis and application of Human Calcitonin Hormone short analogues in treatment of human diseases by gene delivery |
| Arbeitskreis | Prof. Sergey Burov |
| Ort | Department of Industrial Drug Technology, Chemical Pharmaceutical Academy, St. Petersburg, Russland |
Dissertation
| Titel | N-Amidino-amino Acids and their Applications in Synthesis of Polypeptides |
| Arbeitskreis | Prof. Sergey Burov |
| Ort | IMC RAS, St. Petersburg, Russland |
Preise und Auszeichnungen
| 04 | M. Sc. in Chemie mit Auszeichnung |
| 06 | Reisestipendium für 29. European Peptide Symposium |
| 08 | Reisestipendium für 30. European Peptide Symposium |
| seit 08/08 | Mitglied der European Peptide Society |
| 09 – 10 | Stipendium des Russian President Council for young scientists: Development of comprehensive solution and solid-state NMR method for structural analysis of polymer systems |
Publikationen
| 1 |
S. V. Burov, Yu. E. Moskalenko, E. F. Panarin Synthesis of N-[N1-(2,4,6-Trimethylphenylsulfonyl)-carbamimidoyl]-L-proline Russ. J. Gen. Chem. 2006, 76, 665-667. |
| 2 |
S. Burov, Yu. E. Moskalenko, M. Leko, M. Dorosh, Z. Shkarubskaya, E. Panarin Derivatives of N-Amidino-proline and their use in conventional and solid phase peptide synthesis Russ. J. Bioorg. Chem. 2006,32, 509-516. |
| 3 |
Yu. E. Moskalenko, I. N. Dementieva, M. I. Kadinskaya, S. V. Burov The influence of RGD peptides analogues and low-power light-emitting diode irradiation on ADP-induced platelet aggregation Clinical Laboratorial Concilium 2007, 18, 36-40 (in Russian). |
| 4 |
S. Burov, Yu. E. Moskalenko, M. Dorosh, Z. Scharubskaya, E. Panarin Incorporation of N-amidino-pyroglutamic acid into peptides using intramolecular cyclization of α-guanidinoglutaric acid J. Pept. Sci. 2009, 15, 760-766. |
| 5 |
Yu. E. Moskalenko, N. N. Shevchenko, M. V. Mokeev, A. Yu. Men’shikova, A. V. Yakimansky, A. V. Gribanov Solid-state 13C NMR spectroscopic examination of lower alcohol vapor sorption by cross-linked poly(methyl methacrylate) particles Russ. J. Appl. Chem. 2010, 83, 400-405. |
| 6 |
N. A. Bokach, N. P. Konovalova, Y. Wang, Yu. E. Moskalenko, A. V. Gribanov, V. Yu. Kukushkin One-end nucleophilic addition of di- and triamines to PtIV coordinated nitriles as an entry to (amidine)PtIV complexes bearing pendant NH2-groups Dalton Trans. 2010, 39, 4619-4623. |
| 7 |
A. Yu. Men'shikova, Yu. E. Moskalenko, A. V. Gribanov, N. N. Shevchenko, V. V. Faraonova, A. V. Yakimanskii, M. Ya. Goikhman, N. L. Loretsyan, A. V. Koshkin, M. V. Alfimov Sorption of vapors of aromatic compounds by cross-linked polymer particles containing luminophores: A spectroscopic study Russ. J. Appl. Chem. 2010, 83, 1997-2005. |
| 8 |
Yu. E. Moskalenko, A. Yu. Men'shikova, N. N. Shevchenko, V. V. Faraonova, A. V. Gribanov A 1H NMR study of Nile Red solvation High Energy Chem. 2011, 45, 183-187. |
| 9 |
M. Käldström, N. Kumar, M. Tenho, M. Mokeev, Yu. E. Moskalenko, D. Murzin Catalytic transformations of birch kraft pulp, ACS Catal. 2012, 2, 1381-1393. |
| 10 |
Yu. E. Moskalenko, V. Bagutski, C. M. Thiele Chemically synthesized and cross-linked PDMS as versatile alignment medium for organic compounds Chem. Commun. 2017, 53, 95-98. [Inside Front Cover] |
Ausgewählte Poster
| 1 | N-Amidino-proline derivatives and their application in peptide synthesis, Transatlantic Frontiers of Chemistry Meeting, 29th European Peptide Symposium, Gdansk/Poland, 09/06. |
| 2 | Synthesis and conformational analysis of new gonadotropin-releasing hormone (GnRH) analogues, VIth International Symposium “Molecular Order and Mobility in Polymer Systems”, St. Petersburg/Russia, 06/08. |
| 3 | Synthesis of peptides containing five-member cyclic N-amidino-amino acids, 30th European Peptide Symposium, Helsinki/Finland, 08/08. |
| 4 | Conformational isomerisation of PtII-coordinated 1,3,5-triazine in solution and solid state, EUROMAR 2010, Florence/Italy, 07/10. |
| 5 | Drug-polymer interactions of water-soluble chitosan: UV/VIS and NMR spectral investigation, 10th Baltic Polymer Symposium, Palanga/Lithuania, 09/10. |
| 6 | W. Blum, Yu. E. Moskalenko, C. M. Thiele, Design, Synthesis and Evaluation of β-peptides in NMR-RDC-Structural Analysis, Wissenschaftsforum Chemie 2013, Darmstadt, 09/13. |
| 7 | Yu. E. Moskalenko, W. Blum, C. M. Thiele, β-Peptide Liquid Crystalline Phases for NMR/RDC Structural Analysis of Organic Molecules, PepMat 2013: Peptide Materials for Nanotechnology and Biomedicine, Sorrento/Italy, 10/13. |
| 8 | Yu. E. Moskalenko, K. Pulka-Ziach, C. M. Thiele, Desing of Oligoureas Containing Aromatic Side-Chains, 33rd European Peptide Symposium, Sofia/Bulgaria, 09/14. |
| 9 | Yu. E. Moskalenko, V. Bagutski, L. Kaltschnee, C. M. Thiele, PDMS Gels as Alignment Media for NMR/RDC Analysis of Small Organic Molecules: Synthesis and Evaluation, ORCHEM, Weimar, 09/14. |
| 10 | L. Kaltschnee, T. Imhof, K. Pulka-Ziach, Yu. E. Moskalenko, W. Bermel, C. M. Thiele, Improving Signal Separation for Oligomeric Structures in Pure Shift HSQC Spectra, EUROMAR 2015, Prague/Czech Republic, 07/15. |
Vorträge
| 1 | Physicochemical Processes in Polymer Architectures Seen by NMR Spectroscopy at Various Dimension Levels, VIIth International Symposium “Molecular Mobility and Order in Polymer Systems”, St. Petersburg/Russia, 06/11. |