- Medicinal chemistry of Alzheimer`s disease
Fluorescent probes for in vivo microscopy/ Alzheimer Diagnostics
Project presentation Deutsche Welle 13.2.2011 (min 3-8)
Podcast:
2 h HBO documentary on Alzheimer's disease research
- medicinal chemistry of:
hypertension: Angiotensin II receptor blocker
Alzheimer’s disease:: , β-secretase inhibitors, diagnostics, Tau Aggregation inhibitors, GSK3 inhibitors, fluorescent probes for Alzheimer diagnostic applications Parkinson’s disease Creutzfeld-Jacob disease: Prion aggregation inhibitors oncology: β-secretase inhibitors 20 S proteasome inhibitors
- multiparallel solid phase supported synthesis of non-peptidic lead structures
- selective aspartic protease modulators and inhibitors
- novel screening technologies
- drug metabolism
- reaction mechanisms: enantioselective reactions, metal-organic reactions
- protein-peptide interactions: beta-sheet aggregation
- heterocycle synthesis: novel heterocycles, green reactions
- novel reaction media: reactions in ionic liquids
- screening in fish