Johann Primozic – Thiele Lab – TU Darmstadt

The Thiele group

Picture: P. Czechowski, www.czeko.de

Dr. Johann Primozic

Working area(s)

Bachelor thesis 04/16 - 07/16, Student assistant 08/17 - 09/17, Master thesis 04/18 - 10/18, PhD thesis 12/18 - 12/23

Contact

Field of research

Investigation of reaction mechanisms using modern NMR spectroscopy
Structure elucidation of reactive intermediates

Education

00 – 13	Primary and Secondary School, Groß-Umstadt
10/13 – 09/16	Bachelor of Science in Chemistry, Technische Universität Darmstadt, Darmstadt
10/16 – 02/17	Scientific Practical Course, Università degli Studi di Sassari, Sassari/Italy, with Prof. Dr. Ugo G. Azzena
10/16 – 10/18	Master of Science in Chemistry, Technische Universität Darmstadt, Darmstadt
04/18 – 10/18	Master's thesis project, School of Chemistry, University of Edinburgh, Edinburgh/Scotland, with Prof. Dr. Guy C. Lloyd-Jones FRS
12/18 – 12/23	PhD Programme in Chemistry, Technische Universität Darmstadt, Darmstadt

Bachelor thesis

Title	Influence of Decomposition Reactions on the Enantiodifferentiating Properties of PBDG
Group	Prof. Dr. C. M. Thiele
Place	Department of Chemistry, Technische Universität Darmstadt

Master thesis

Title	Mechanistic Investigation of the gem-Difluorocyclopropanation of Alkenes by TMSCF₃
Group	Prof. Dr. G. C. Lloyd-Jones FRS, Prof. Dr. C. M. Thiele
Place	School of Chemistry, University of Edinburgh, Edinburgh; Clemens-Schöpf-Institut für Organische Chemie und Biochemie, Fachbereich Chemie, Technische Universität Darmstadt

Dissertation

Title	Mechanistic Investigation of the Diastereodivergent Asymmetric Allylic Alkylation of Cyclobutenes
Group	Prof. Dr. C. M. Thiele
Place	Department of Chemistry, Technical University Darmstadt

Prizes and awards

10/17 – 09/18	Deutschlandstipendium
03/18 – 10/18	Otto-Bayer-Scholarship, Bayer Science & Education Foundation
08/19 – 08/21	Kekulé-PhD-Fellowship, Chemical Industry Fund (FCI)

Publications

1	D. Sinnaeve,* J. Ilgen, M. E. Di Pietro, J. J. Primozic, V. Schmidts, C. M. Thiele, B. Luy Probing long-range anisotropic interactions – A general and sign-sensitive strategy to measure ¹H-¹H residual dipolar couplings as a key advance for organic structure determination Angew. Chem. Int. Ed. 2020, 59, 5316-5320; Angew. Chem. 2020, 132, 5354-5358. [Raw Data: DOI 10.6084/m9.figshare.11297651]
2	A. García-Domínguez, T. H. West, J. J. Primozic, K. M. Grant, C. P. Johnston, G. G. Cumming, A. G. Leach, G. C. Lloyd-Jones* Difluorocarbene Generation from TMSCF₃: Kinetics and Mechanism of NaI-Mediated and Si-Induced Anionic Chain Reactions J. Am. Chem. Soc. 2020, 142, 14649–14663.
3	J. J. Primozic, J. Ilgen, P. Maibach, M. Brauser, J. Kind, C. M. Thiele* Pd-Catalyzed Asymmetric Allylic Alkylation of Cyclobutenes: From Double Inversion to Double Retention J. Am. Chem. Soc. 2023, 145, 15912-15923.

Poster

1	S. Weißheit, J. J. Primozic, C. M. Thiele How Acidic Decomposition Products of CDCl₃ Influence the Orientational Properties of Alignment Media EUROMAR 2016, Aarhus/Denmark, 07/16.
2	J. J. Primozic, T. H. West, G. C. Lloyd-Jones Mechanistic Insight into the Anion-Initiated gem-Difluorocyclopropanation of Alkenes by TMSCF₃: Partition as Key Feature 691. WE-Heraeus-Seminar on “Physical Organic Chemistry: Recent developments in instrumentation, structure, theory, and mechanisms", Bad Honnef, 02/19.
3	J. J. Primozic, C. M. Thiele Diastereodivergent Asymmetric Allylic Alkylation of Cyclobutenes: Kinetics and HPLC-MS Studies International Symposium on Synthesis and Catalysis 2021, Évora/Portugal, 09/21.
4	J. J. Primozic, J. Ilgen, P. Maibach, Christina M. Thiele Diastereodivergent Asymmetric Allylic Alkylation of Cyclobutenes: A Challenging Mechanistic Puzzle Balticum Organicum Syntheticum, Vilnius/Lithuania, 07/22.