Structure-based Drug Research

Our group draws from the cooperation between synthetic chemists preparing novel, rationally designed compounds and biochemists who investigate new molecular mechanisms of action.

Fields of study

Rational Drug Design
Identification and validation of novel pharmacological concepts
Synthesis of macro- or polycyclic substances to control the bioactive conformation
Proximity-based tools and approaches
Development of FKBP51 inhibitors as novel antidepressants, analgesics or anti-obesity agents
Allosteric modulation of G protein coupled receptors

LEAF certification

We are proud to be part of the LEAF program that certifies sustainable Labs.

We entered the program 2023 and strive to reduce our ecological footprint further in the future.

The Faculty

The Research Group Hausch is part of the Forschungsbereich Biochemie:

Conformation sensitive Mass Spectrometry (Prof. Dr. Frederik Lermyte) RG Lermyte
Applied Biochemistry (Prof. Dr. Harald Kolmar) RG Kolmar
Biological Chemistry (Prof. Dr. Katja Schmitz)RG Schmitz
Structure-Based Drug Research (Prof. Dr. Felix Hausch)

The Research Group Hausch is located in the building L2|02, 4th floor of the Department of chemistry, in the TU-Lichtwiese Campus of the TU Darmstadt (rooms A401-A409). The office hours of the secretary Ms Barbara Diestelmann are Monday-Thursday from 9:00-13:00 at A409 (telephone 16-21290) and from 14:00-17:00 at C465 (telephone 16-21230)Email