Jan Rettig
Working area(s)
Bachelor thesis 04/18 - 07/18, M.Sc. thesis 03/20 - 09/20, PhD thesis 12/20 -
Contact
jrettig@thielelab.de
Field of research
- relative configuration determination using RDCs, NOEs and J couplings
- synthesis, purification and application of peptide-based alignment media
Education
| 06/15 | High school graduation, Gymnasium Gernsheim, Gernsheim |
| 10/15 – 09/18 | Study of Chemistry (B.Sc.), Technische Universität Darmstadt, Darmstadt |
| 10/18 – 09/20 | Study of Chemistry (M.Sc.), Technische Universität Darmstadt, Darmstadt |
Bachelor thesis
| Title | Measurement of a complete RDC data set of Isopinocampheol |
| Group | Prof. Dr. C. M. Thiele |
| Place | Department of Chemistry, Technical University Darmstadt |
Master thesis
| Title | Determination of the relative configuration of a polysubstituted hydrindane |
| Group | Prof. Dr. C. M. Thiele |
| Place | Clemens-Schöpf-Institut für Organische Chemie und Biochemie, Fachbereich Chemie, Technische Universität Darmstadt |
Prizes and awards
| 10/19 – 09/20 | Student fellowship (Deutschlandstipendium) |
| 04/21 | Award of the Dr.-Anton-Keller-Foundation at Technische Universität Darmstadt |
| 08/21 – 08/23 | Kekulé-PhD-Fellowship, Chemical Industry Fund (FCI) |
| 07/2023 | Best Poster Award, Chirality 2023, Rom/Italy |
Publications
| 1 |
F. A. Roth, V. Schmidts, J. Rettig, C. M. Thiele Model Free Analysis of Experimental Residual Dipolar Couplings in Small Organic Compounds Phys. Chem. Chem. Phys. 2022, 24, 281-286. [Raw Data: 10.5281/zenodo.5636052, Pre-Print: 10.26434/chemrxiv.14636316.v1] |
| 2 |
Editors: L. Yao, B. Vogeli Residual Dipolar Couplings: Principles and Applications J. Rettig, M. Brauser, C. M. Thiele Chapter 11: Structure Determination of Organic Molecules Using RDCs (and RCSAs) RSC 2024, ISBN: 978-1-83916-429-3, 252-279. |
| 3 |
F. Trauner, R. Ghazali, J. Rettig, C. M. Thiele, D. Didier* Stereoselective polar radical crossover for the functionalization of strained-ring systems Commun. Chem. 2024, 7, 134. [Supplementary Data: 10.6084/m9.figshare.25907506] |
| 4 |
J. Rettig, M. Gölz, C. M. Thiele Synthesis and Application of a Hydrophobic Polyglutamate Bearing a Triphenylphosphine Group for the Orientation of Pharmaceutically Active Compounds and the Measurement of Residual Dipolar Couplings Magn. Reson. Chem., 2025, 10.1002/mrc.5522 |
presentations
| 1 |
Application of a Novel Triphenylphosphine-bearing Alignment Medium to Elucidate the Structures of Pharmaceutical Compounds EUROMAR 2024, Bilbao/Spain, 07/24 (upgraded poster). |
Poster
| 1 |
J. Rettig, C. M. Thiele Lyotropic Liquid Crystals (LLCs) and Residual Dipolar Couplings (RDCs) – A Dream Team German Liquid Crystal Conference (GLCC) 2022, Würzburg, 03/22. |
| 2 |
J. Rettig, L. Neumann, E. Stempel, T. Tautz, M. Kalesse, C. M. Thiele Thorough NMR-based structure elucidation of diastereomeric compounds synthesized with surprisingly high selectivity ORCHEM 2022, Münster, 09/22. |
| 3 |
J. Rettig, T. Tautz, E. Stempel, M. Kalesse, C.M. Thiele Determination of relative configurations of diastereomeric compounds bearing a flexible, quarternary stereocenter by NMR spectroscopy Chirality 2023, Rom/Italy, 07/23. |
| 4 |
J. Rettig, T. Tautz, E. Stempel, M. Kalesse, C.M. Thiele The inherent challenges posed by a quaternary, exocyclic stereocenter in structure elucidation using RDCs SMASH 2023, Baveno/Italy, 09/23. |
